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				<title><![CDATA[Best Penis Enlargement Articles - Articles]]></title>
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					  <title><![CDATA[Viagra Benefits Men With Heart Failure]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1699/1/Viagra-Benefits-Men-With-Heart-Failure/Page1.html</link>
					  <description><![CDATA[
Men with congestive heart failure and erectile dysfunction (ED) safely used sildenafil (Viagra) to improve sexual function in a study reported in today's rapid access issue of Circulation: Journal of the American Heart Association. The popular medication may even make patients more likely to take their heart failure drugs, says author Edimar Alcides Bocchi, M.D., associate professor and chief of the heart failure clinics at the Sao Paulo University Medical School in Brazil. 
&#34;Heart failure patients may become noncompliant with their congestive heart failure (CHF) treatment if they feel it causes or aggravates their ED,&#34; Bocchi says. &#34;However, our study suggests that treating the ED may make patients more motivated to take their medicines.&#34; 
Sildenafil caused no harmful effects and improved exercise performance during treadmill exercise tests in 23 men with CHF (average age 50) and a history of ED, says Bocchi. 
Sildenafil blocks the activity of the enzyme phosphodiesterase type 5 (PDE5), which is active in multiple tissues and cells. The effects of PDE5 inhibition include increased production of nitric oxide, which is associated with improved function of the heart and blood vessels. 
The cardiovascular effects of sildenafil have created some concern that the drug might be harmful in men with CHF. But there's not enough data on the safety or potential harm of sildenafil in CHF patients. 
Most of the men had moderate or severe heart failure, and each had been referred for treatment of ED. On separate days, the men underwent two exercise treadmill tests, which consisted of a six-minute walk and a maximal exercise test. About an hour before the first test, the men received either 50 milligrams of sildenafil or a placebo. On the second day, the men received the opposite treatment (sildenafil or placebo) before exercise. 
Those treated with sildenafil had significantly lower blood pressure and heart rate and improvement in measures of oxygen consumption and carbon dioxide production compared with those on placebo. Total exercise time also increased significantly. A separate evaluation showed that treatment with sildenafil was associated with higher scores on a questionnaire related to erectile function. 
&#34;Frequently, CHF patients, and especially their wives, are afraid their spouses will have heart failure symptoms or even death during sexual activity,&#34; says Bocchi. &#34;Our study shows that the benefits may outweigh harmful side effects of treatment with sildenafil. The successful treatment of ED in CHF could not only improve sexual relationships but overall quality and success of CHF treatment.&#34; 





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					  <author>peter78b@gmail.com (Linda Lewis)</author>
					  <pubDate>Mon, 05 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Study Finds Eyes Unaffected By Viagra]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1698/1/Study-Finds-Eyes-Unaffected-By-Viagra/Page1.html</link>
					  <description><![CDATA[
 When Viagra was introduced several years ago, the drug's manufacturer warned of a number of visual side effects, including possible nerve damage to the eyes. But a UC Irvine College of Medicine study rules out some of these risks - even when the drug is taken in high doses. 
According to Dr. Tim McCulley, assistant professor of ophthalmology, blood flow in the eye does not seem to be reduced by even high doses of the popular erectile dysfunction drug. Since Viagra lowers blood pressure overall, there was persistent suspicion that the drug might cause decreased optical blood flow, which can cause nerve damage. 
McCulley's study appears in the January 2003 issue of Ophthalmologica. 
&#34;Viagra can change blood vessel structure as well as general blood pressure, so we needed to answer the question whether the drug could change blood vessels in the eye,&#34; McCulley said. &#34;Our study may have had a small group of participants, but it showed very little change in blood vessels or blood flow in nearly all the patients.&#34; 
McCulley's team conducted the trial at Stanford University and found that high doses of Viagra by and large preserved the thickness of the eye's choroids layer, which supplies the eyeball with blood. However, the team did find some small variations in thickness, which indicated that some people with underlying vascular diseases may indeed have changes in vision. 
In addition, the researchers found no connection among blood flow choroid thickness and changes in color vision, a common side effect of taking Viagra. 
McCulley's team confirmed these side effects, finding that Viagra users had a harder time discriminating among subtle changes in color. But they also found that Viagra users reported problems in picking out any number of colors, not just the blue-green variety reported during the drug's clinical trials. 








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					  <author>peter68b@gmail.com (Rogger Miller)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Puzzling Viagra Deaths Explained]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1697/1/Puzzling-Viagra-Deaths-Explained/Page1.html</link>
					  <description><![CDATA[
Since its introduction, 564 deaths have been linked to the use of the impotence drug Viagra. These incidents of heart attack and stroke have been a puzzle. After all, Viagra, commonly prescribed for erectile dysfunction, was originally developed to prevent these conditions - not only by dilating blood vessels but also by stopping platelets in the blood from clumping. In fact, the drug does just the opposite, according to researchers at the University of Illinois at Chicago College of Medicine. They found that Viagra, by elevating levels of a compound in cells called cyclic guanosine monophosphate, or cGMP, actually encourages platelets to aggregate. 
The study, to be published in the Jan. 10 issue of the scientific journal Cell, amends 20 years of scientific claims that cGMP acts to prevent platelet aggregation. 
While platelet aggregation helps minimize the loss of blood when injury occurs, it can also lead to clotting that blocks a blood vessel - a life-threatening condition called thrombosis that can cause heart attack and stroke. 
&#34;Viagra, by itself, probably is not sufficient to cause a heart attack in healthy people, but our research suggests that it may present a risk for patients with preexisting conditions such as atherosclerosis,&#34; said Xiaoping Du, associate professor of pharmacology and the study's lead author. 
Du said he and his coworkers had not set out to investigate the cause of fatalities in Viagra patients when they began their research about five years ago. Rather, as a basic research scientist, he was hoping to illuminate the highly complex series of molecular steps that control platelet aggregation. 
Platelets are disk-shaped cells that freely circulate in the blood. When a blood vessel is injured, the platelets form sticky surfaces, adhering to one another and to the damaged area to plug the hole. 
Using recombinant DNA techniques, the researchers forced standard laboratory cells to manufacture two proteins key to platelet aggregation: one that helps the platelets clump together and stick to the surface of broken blood vessels, and another that activates the first. The genetic manipulation enabled the researchers to isolate and study the molecules that trigger these proteins. 
Du focused on PKG, or cGMP-dependent protein kinase. 
&#34;It was accepted knowledge that cGMP, by stimulating PKG-catalyzed reactions in platelets, inhibits their clumping,&#34; said Du. To his astonishment, he and his colleagues found otherwise. 
&#34;When we put PKG into the recombinant cells, we found that we actually made the cells more adherent,&#34; Du said. 
The results were so surprising that the researchers wondered whether there was something special about the laboratory cells that made them react differently. But tests in mouse and human platelets yielded the same results. Moreover, platelets from mice incapable of manufacturing PKG failed to aggregate as well as platelets from normal mice. 
Reconciling their findings with earlier scientific evidence that cGMP inhibits platelet aggregation, the UIC researchers believe that cGMP initially causes platelets to clump to seal a wound, but later reverses to stop an excessive buildup of cells that might block a blood vessel. If a person were at risk of thrombosis - if, for instance, a damaged blood vessel were already narrowed - even the initial accumulation of platelets could be sufficient to cause a problem. 
Since Viagra is known to work by inhibiting an enzyme that breaks down cGMP, and hence raises its level, Du and his colleagues tested the drug on platelets taken from normal donors. Alone, Viagra did not promote platelet aggregation, but it did so in the presence of a small amount of other compounds typically present when a blood vessel is damaged. In fact, Viagra caused the cells to clump at concentrations well below those achieved in patients prescribed the drug for erectile dysfunction. 
An estimated 16 million men worldwide have taken Viagra. 











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					  <author>enlargepenisguide.com@gmail.com (Richard Luong)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Erection Goes Up In Smoke]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1696/1/Erection-Goes-Up-In-Smoke/Page1.html</link>
					  <description><![CDATA[
 Cigarette smoking significantly increases the risk of erectile dysfunction, according to a study reported today at the American Heart Association's 43rd Annual Conference on Cardiovascular Disease Epidemiology and Prevention. 
Men who smoked more than 20 cigarettes daily had 60 percent higher risk of erectile dysfunction, compared to men who never smoked. The data showed a dose-related impact of smoking: the risk of erectile dysfunction was lower in men who smoked fewer cigarettes, but still increased compared to non-smokers. 
The effect of smoking remained significant after considering other factors known to affect erectile function such as age, blood pressure, cholesterol levels, diabetes and body mass index (BMI). 
&#34;This is not the first study to document an association between cigarette smoking and erectile dysfunction,&#34; says Jiang He, M.D., Ph.D., Steward Associate Professor of Epidemiology and Medicine at Tulane University School of Public Health and Tropical Medicine in New Orleans. &#34;However, our study is very unique because it is able to adjust for important confounders, such as blood pressure, serum cholesterol, and diabetes.&#34; 
Erectile dysfunction is often associated with atherosclerosis, the build-up of wax-like plaque that obstructs blood flow through vessels. Smoking is a well-recognized risk factor for cardiovascular disease and studies have shown there are strong parallels and shared risks among smoking, coronary artery disease, atherosclerosis, and erectile dysfunction, says He. 
Researchers examined data on 4,764 Chinese men (average age 47) involved in the InterASIA study, a national cross-sectional health survey conducted during 2000-2001. The survey included questions about respondents' current smoking status and history and quality of sexual relations. All men reported having sexual relations within the past six months. 
Survey respondents were defined as current smokers if they were smoking at the time of the survey and had smoked at least 100 cigarettes in their lifetime. Former smokers were defined as having smoked more than 100 cigarettes in their lifetime but were not smoking at the time of the survey. 
The average blood pressure and cholesterol values for the men were within normal ranges, and the average body mass index (BMI, an indicator of weight and body size) indicated the men were not overweight as a group. Of the survey respondents, 62.1 percent were current smokers, and 9.5 percent were former smokers. 
Overall, 14.6 percent of the men experienced erectile dysfunction. Current and former smokers had identical rates of 15.1 percent, and the rate among men who had never smoked was 11.5 percent. After statistically accounting for other erectile function influences, researchers found that current smokers had a 31 percent higher risk for dysfunction compared to men who had never smoked. A similar difference was seen in former smokers, who had a 35 percent higher risk. 
&#34;We did not see a difference between current and former smokers,&#34; He says. &#34;However, the number of former smokers is small in this study.&#34; 
Focusing on current smokers, researchers evaluated the impact of increasingly heavy cigarette smoking on erectile dysfunction. Men who reported smoking fewer than 10 cigarettes a day had a 16 percent higher risk of erectile dysfunction, compared to men who had never smoked. The risk increased to 36 percent in men who reported smoking 11-20 cigarettes daily and was 60 percent higher in men who smoked more than 20 cigarettes (one pack) daily. 
The findings build on and strengthen data from other studies suggesting that cigarette smoking is a risk factor for erectile dysfunction. 
&#34;These findings provide additional information that smoking has important adverse health effects,&#34; says Robert O. Bonow, M.D., president of the American Heart Association. &#34;This gives male smokers another reason to kick the habit, and provides another area of emphasis and education for smoking cessation programs.&#34; 














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					  <author>peter78b@gmail.com (Peter Hill)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Collagen Implants Regenerate Penis]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1695/1/Collagen-Implants-Regenerate-Penis/Page1.html</link>
					  <description><![CDATA[
Researchers at Children's Hospital Boston report an important advance in tissue engineering of the penis, raising hopes that men with severe impotence - due to penile trauma, surgery, cancer, congenital malformations or other conditions - may someday be able to regain sexual function. 
These findings, presented to the American Urological Association, have implications for men who need reconstruction of the penis, and for men whose penis is intact but has suffered nerve damage - such as men who have undergone radical surgery for prostate cancer. 
Although the body of the penis can be grown in the lab through tissue engineering using smooth muscle cells, the organ needs a working network of nerves in order to achieve erection and function sexually. This animal study, led by Anthony Atala, MD, director of Tissue Engineering at Children's Hospital Boston, showed that implantation of engineered tissue made of collagen can coax nerves to regenerate in the penis. 
The investigators cut the cavernosal nerves - the two bundles of nerves innervating the penis - in 90 rats. At the injury site, they implanted either a graft of the rats' own nerves, or a graft made from collagen, a natural protein found in connective tissue. Some severed nerves were left untreated. The collagen grafts had been engineered to form a channel shape, similar to the natural sheath of a nerve, and follow-up studies three months later showed that the rats' own nerve cells had regenerated and infiltrated this &#34;scaffolding&#34; material. &#34;We used the body's own healing abilities to create the tissue,&#34; explains Atala. 
The degree of nerve regeneration with the collagen grafts equaled that of both normal, undamaged nerves, and the grafts consisting of the rats' own nerves. The severed nerves that were left untreated showed no signs of regeneration. 
Atala's lab previously showed that the tissue making up the body of the penis can be successfully grown in the lab, and successfully used to reconstruct the penises of rabbits that had part of the organ surgically removed. This new study takes penile reconstruction a step further; showing that the nerves required for erectile function can be induced to grow through tissue engineering. 
&#34;Right now we can do partial penile repair, but in order to do complete replacements, we need to make sure all the parts are there, including the nerves,&#34; Atala said. &#34;This research takes us one step closer.&#34; Future work will attempt to tissue-engineer a complete penis, growing the body of the organ and providing it with a functioning set of nerves. 




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					  <author>peter68b@gmail.com (Michelle Ryan)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Impotence And Heart Disease Linked]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1694/1/Impotence-And-Heart-Disease-Linked/Page1.html</link>
					  <description><![CDATA[
Preliminary findings from clinicians at the Research Institute of the McGill University Health Centre (MUHC), show that men with erectile dysfunction are more likely to have cardiovascular disease. Cardiovascular disease affects approximately 40,000 Canadian men annually. 
&#34;Our study suggests, that erectile dysfunction, particularly in young men, may be an early warning sign of heart disease and stroke,&#34; says MUHC Director of Clinical Epidemiology, Dr. Steven Grover. 
Dr. Grover, who is also a professor in the Faculty of Medicine at McGill University, and his colleagues evaluated more than 4 000 men. They compared the risk of erectile dysfunction among patients with and without cardiovascular disease. &#34;We found that the presence of cardiovascular disease was strongly associated with erectile dysfunction,&#34; says Dr. Grover. 
Among men without diagnosed cardiovascular disease, cardiovascular risk factors such as diabetes, smoking, high blood pressure and low HDL cholesterol were more common among those who had erectile dysfunction. This suggests that the men who have erectile dysfunction and have no other symptoms of cardiovascular disease may be at increased risk for developing the disease. Grover said that a complete diagnostic evaluation of erectile dysfunction should include screening for cardiovascular risk factors. 

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					  <author>peter78b@gmail.com (Linda Lewis)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Impotence Can Be Symptom Of Serious Illness]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1693/1/Impotence-Can-Be-Symptom-Of-Serious-Illness/Page1.html</link>
					  <description><![CDATA[
Erectile dysfunction (impotence), is no longer the taboo topic it once was, perhaps due to Viagra, the first oral drug for this condition. Whilst new drugs like Viagra have raised awareness of impotence, it is important for men to understand that impotence may be a symptom of other illnesses. Impotence can be the first sign of serious illnesses including diabetes; high blood pressure; kidney, liver or hormonal disorders; or coronary artery disease. 
The current issue of the Mayo Clinic Health Letter outlines other treatment options for erectile dysfunction and why treatment is important. 
Erectile dysfunction is more common in men over age 65 but can occur at any age. Men with concerns about impotence should ask their doctor about treatment options which include; 



Oral medications: As well as Viagra, a second medication was approved by the FDA in 2003 and another is expected to be available by the end of the year. 

Injected drugs: Men can inject drugs into the penis to enhance blood flow. 

Self-administered intraurethral therapy: This involves using a small applicator to insert a tiny pellet of medicine into the urethra. 

Vacuum devices: These devices are a hollow plastic tube which is placed over the penis and pumped to create a vacuum that pulls blood into the penis. 

Surgical options: These are usually considered if other treatments aren't working. Semirigid rods or inflatable devices may be surgically implanted. 

The Mayo Clinic Health Letter is an eight-page monthly newsletter of information on today's health and medical news. To subscribe, please call toll-free 800-333-9037, extension 9PR1.

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					  <author>peter68b@gmail.com (Rogger Miller)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
					 <guid isPermaLink="true">http://www.enlargepenisguide.com/articles/articles/1693/1/Impotence-Can-Be-Symptom-Of-Serious-Illness/Page1.html</guid>
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					  <title><![CDATA[Diet &#38; Exercise A Better Option For Erectile Dysfunction]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1692/1/Diet--Exercise-A-Better-Option-For-Erectile-Dysfunction/Page1.html</link>
					  <description><![CDATA[
Obese men with erectile dysfunction may be able to improve their sexual function with exercise and weight loss, according to a study appearing in The Journal of the American Medical Association. Erectile dysfunction is a leading cause of decreased quality of life in men and may affect as many as 30 million men in the U.S. In a previous study, moderate-to-severe erectile dysfunction was reported by 12 percent of men younger than 59 years; 22 percent of men aged 60 to 69 years; and 30 percent of men older than 69 years. 
Katherine Esposito, of the Center for Obesity Management in Naples, Italy, and colleagues conducted a study to determine if lifestyle changes designed to obtain a sustained and long-term reduction in body weight and an increase in physical activity would improve erectile function in obese men. 
The men involved in the study received detailed advice about how to achieve a loss of 10 percent or more in their total body weight by reducing caloric intake and increasing their level of physical activity. 
The researchers said, &#34;Our data demonstrate that lifestyle changes, including a reduced calorie diet and increased exercise, improve erectile function in obese men and resulted in about one-third of men with erectile dysfunction regaining sexual function after treatment. This improvement was associated with amelioration of both endothelial function and markers of systemic vascular inflammation. Interventions focused on modifiable health behaviors may represent a safe strategy to improve erectile function and reduce cardiovascular risk in obese patients.&#34; 
Christopher S. Saigal of the University of California echoed the researchers views, &#34;At a time in which obesity has become a public health crisis, this study provides evidence of efficacy for what perhaps should be the first-line treatment for obese patients with erectile dysfunction. This treatment strategy produces many benefits for the patient if it is successful and incurs no untoward risk if it is not. Unfortunately, however, this is one treatment for erectile dysfunction that will not be accompanied by free pens, free notepads, and its own Super Bowl commercial.&#34; 




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					  <author>enlargepenisguide.com@gmail.com (Richard Luong)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Combination Treatment For Low Testosterone Men]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1691/1/Combination-Treatment-For-Low-Testosterone-Men/Page1.html</link>
					  <description><![CDATA[
Men suffering erectile dysfunction and low testosterone who do not respond to Viagra&#174; (sildenafil citrate) alone may benefit from the supplemental use of AndroGel&#174;, a testosterone gel. The combination was found to improve erectile function and overall sexual satisfaction in a Columbia University Medical Center study, published in the Journal of Urology. 
&#34;Our data support the potential benefits of a combination therapy with testosterone gel for men with erectile dysfunction and low testosterone who find sildenafil by itself ineffective,&#34; said Dr. Shabsigh of Columbia University. &#34;When assessing erectile dysfunction, doctors and patients should consider using a simple blood test to determine if low testosterone is a contributing factor. If the root cause is low testosterone, sildenafil alone won't fix the problem.&#34; 
It is estimated that four to five million American men have low testosterone (hypogonadism). Low testosterone may lead to decreased libido, erectile dysfunction, osteoporosis, reduced lean body mass and fatigue. 
Sildenafil enhances the effects of nitric oxide, a chemical in the body that allows increased blood flow to the penis during sexual stimulation. &#34;Research suggests nitric oxide may be dependent on testosterone to function properly,&#34; said Dr. Shabsigh. &#34;While further studies are needed, this concept may explain why testosterone replacement therapy could help hypogonadal men who do not respond to sildenafil.&#34;Thanks to : Penis Pills

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					  <author>peter78b@gmail.com (Peter Hill)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
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					  <title><![CDATA[Erection Problems May Be Early Warning Of Heart Attack]]></title>
					  <link>http://www.enlargepenisguide.com/articles/articles/1690/1/Erection-Problems-May-Be-Early-Warning-Of-Heart-Attack/Page1.html</link>
					  <description><![CDATA[
In the lead up to Valentine's Day, the American Urological Association is cautioning men that poor quality erections or erectile dysfunction could be an early warning sign that heart disease is threatening. Urologists define erectile dysfunction as the inability of a man to attain and maintain an erection sufficient for sexual intercourse. Studies of men who were diagnosed with ischemic heart disease (lack of sufficient blood flow to the heart) found that a significant number of these men reported having erectile problems an average of more than four years prior to developing actual heart-related complaint. 
&#34;It's an important indicator,&#34; says Dr. Ira Sharlip, at the University of California. &#34;Erections depend on blood flow, so if there is a problem with blood flow to the penis, what these studies say is that reduced blood flow due to arteriosclerosis may exist in other parts of the circulatory system and could lead to heart disease or heart attack. Men need to recognize that the circulatory system is responsible for many components of overall health, and that erectile dysfunction, which some men find difficult or embarrassing to discuss with their doctors, should be taken seriously because erectile dysfunction may be a warning sign of even more serious illness.&#34; Thanks to : Penis Pills]]></description>
					  <author>peter68b@gmail.com (Michelle Ryan)</author>
					  <pubDate>Fri, 02 May 2008 00:00:00 -0700</pubDate>
					 <guid isPermaLink="true">http://www.enlargepenisguide.com/articles/articles/1690/1/Erection-Problems-May-Be-Early-Warning-Of-Heart-Attack/Page1.html</guid>
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